Wen-Feng Zhang Selected Research

Immune Checkpoint Proteins

10/2019	Blockade of TIGIT/CD155 Signaling Reverses T-cell Exhaustion and Enhances Antitumor Capability in Head and Neck Squamous Cell Carcinoma.
8/2018	Over-expression of IQGAP1 indicates poor prognosis in head and neck squamous cell carcinoma.
1/2018	Expression and phosphorylation of Stathmin 1 indicate poor survival in head and neck squamous cell carcinoma and associate with immune suppression.
1/2018	γ-Secretase inhibitor reduces immunosuppressive cells and enhances tumour immunity in head and neck squamous cell carcinoma.
1/2017	Selective blockade of B7-H3 enhances antitumour immune activity by reducing immature myeloid cells in head and neck squamous cell carcinoma.
1/2016	LAG-3 confers poor prognosis and its blockade reshapes antitumor response in head and neck squamous cell carcinoma.

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Wen-Feng Zhang Research Topics

Disease

37	Neoplasms (Cancer) 03/2021 - 01/2006
37	Squamous Cell Carcinoma of Head and Neck 01/2020 - 01/2015
7	Neoplasm Metastasis (Metastasis) 06/2019 - 12/2008
6	Adenoid Cystic Carcinoma (Cylindroma) 09/2015 - 01/2012
5	Carcinogenesis 01/2020 - 12/2015
5	Hemangioma (Angioma) 05/2013 - 05/2006
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2017 - 12/2008
4	Hypoxia (Hypoxemia) 03/2016 - 01/2006
3	Inflammation (Inflammations) 05/2017 - 11/2016
3	Pleomorphic Adenoma 01/2015 - 01/2014
2	Hypertension (High Blood Pressure) 07/2020 - 01/2020
2	Lymphatic Metastasis 01/2018 - 01/2016
2	Head and Neck Neoplasms (Head and Neck Cancer) 03/2017 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 11/2016 - 02/2013
2	Carcinoma (Carcinomatosis) 09/2015 - 12/2008
2	Mouth Neoplasms (Oral Cancer) 10/2007 - 07/2006
1	Virus Diseases (Viral Diseases) 03/2021
1	Anorexia 01/2020
1	Disease Progression 01/2020
1	COVID-19 01/2020
1	Coinfection 01/2020
1	Fatigue 01/2020
1	Fever (Fevers) 01/2020
1	Prostatic Neoplasms (Prostate Cancer) 01/2019
1	Melanoma (Melanoma, Malignant) 01/2019
1	Starvation 01/2019
1	Glioma (Gliomas) 09/2017

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 10/2020 - 07/2008
7	Transforming Growth Factor-beta Type I ReceptorIBA 11/2018 - 01/2015
6	Immune Checkpoint ProteinsIBA 10/2019 - 01/2016
6	SurvivinIBA 01/2017 - 02/2013
5	Monoclonal AntibodiesIBA 03/2018 - 01/2016
4	NSC 74859IBA 01/2017 - 12/2015
3	Biomarkers (Surrogate Marker)IBA 06/2019 - 01/2015
3	Pharmaceutical PreparationsIBA 04/2017 - 01/2015
3	Cisplatin (Platino)FDA LinkGeneric 03/2016 - 04/2015
2	Long Noncoding RNAIBA 01/2020 - 06/2019
2	MicroRNAs (MicroRNA)IBA 01/2019 - 05/2017
2	Dasatinib (BMS 354825)FDA Link 11/2018 - 03/2017
2	src-Family KinasesIBA 11/2018 - 03/2017
2	p21-Activated KinasesIBA 05/2018 - 01/2016
2	Folic Acid (Vitamin M)FDA LinkGeneric 03/2018 - 01/2017
2	Mucin-3IBA 03/2018 - 01/2017
2	Immunoglobulins (Immunoglobulin)IBA 03/2018 - 01/2017
2	InflammasomesIBA 01/2018 - 01/2017
2	Cetuximab (Erbitux)FDA Link 03/2016 - 01/2015
2	Docetaxel (Taxotere)FDA Link 03/2016 - 12/2015
2	Fluorouracil (Carac)FDA LinkGeneric 03/2016 - 12/2015
2	ErbB Receptors (EGF Receptor)IBA 09/2015 - 01/2015
2	Cyclin D1IBA 04/2015 - 01/2015
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2008 - 01/2006
1	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2020
1	C-Reactive ProteinIBA 07/2020
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 07/2020
1	EnzymesIBA 01/2020
1	lactate dehydrogenase C4IBA 01/2020
1	CreatinineIBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	Histocompatibility Antigens Class IIBA 01/2020
1	Urea (Carbamide)FDA LinkGeneric 01/2020
1	Phosphotransferases (Kinase)IBA 01/2020
1	Oxygen (Dioxygen)IBA 01/2020
1	NitrogenIBA 01/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020
1	AlbuminsIBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	CateninsIBA 01/2020
1	Therapeutic UsesIBA 10/2019
1	Glycoproteins (Glycoprotein)IBA 07/2019
1	IgA receptor (protein B)IBA 07/2019
1	leukocyte-associated immunoglobulin-like receptor 1IBA 01/2019
1	Circular RNAIBA 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	Glucose OxidaseIBA 01/2019
1	Silicon Dioxide (Silica)FDA LinkGeneric 01/2019
1	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 08/2018
1	PhosphoproteinsIBA 05/2018
1	Galectins (Galectin)IBA 03/2018
1	Serine (L-Serine)FDA Link 01/2018
1	AntibodiesIBA 01/2018
1	alpha- cyano- (3,4- dihydroxy)- N- benzylcinnamideIBA 01/2018
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 01/2018
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2018
1	StathminIBA 01/2018
1	GoldIBA 01/2018
1	Adenosine (Adenocard)FDA LinkGeneric 01/2018
1	InterleukinsIBA 01/2018
1	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 01/2018
1	Polysaccharides (Glycans)IBA 09/2017
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 04/2017
1	ParaffinIBA 04/2017
1	TNF Receptor-Associated Factor 1IBA 04/2017
1	Aldehyde Dehydrogenase 1 FamilyIBA 04/2017

Therapy/Procedure

10	Therapeutics 01/2019 - 01/2007
9	Immunotherapy 03/2021 - 12/2015
6	Drug Therapy (Chemotherapy) 09/2016 - 01/2012
2	Radiotherapy 04/2015 - 01/2015
2	Myocutaneous Flap 10/2007 - 07/2006
1	Photothermal Therapy 01/2018
1	Lasers (Laser) 01/2018